The Application Progress of MicroRNA in Cerebral Ischemia-reperfusion Injury

Yuan ZHANG, Ke MENG, Ying XING

Abstract


Ischemia-reperfusion injury (I/R) is caused by the blood flow obstruction and is
further aggravated by restoration of the blood supply suddenly. The brain is the most sensitive organ in the human body; ischemia can cause irreversible damage to brain cells after a few minutes. Therefore, exploring the prevention and treatment of cerebral ischemia-reperfusion injury are of great significance. In the current studies, scholars have found that microRNAs are closely related to the mechanism of cerebral ischemia-reperfusion injury, and gene therapy based on microRNAs is expected to be a new method for it.


Keywords


Ischemia-reperfusion, Injure, MicroRNA, Gene therapy, Progress


DOI
10.12783/dtbh/icmsb2018/25462

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