Efficacy of Aidi Injection Combined with Chemotherapy in the Treatment of Advanced Epithelial Ovarian Cancer

Cong YE, Jun-Rong WANG, Yu-Bo HU

Abstract


Objective: To study the efficacy, quality of life and side effects of Aidi injection
combined with paclitaxel and cisplatin in the treatment of advanced epithelial ovarian cancer. Methods: 68 cases of advanced epithelial ovarian cancer were randomly divided into 2 groups, observation group and the control group, each group contains 34 cases. The patients in the control group were treated with chemotherapy, and the patients in the observation group were treated with Aidi injection combined with chemotherapy. We evaluated the efficacy and toxic
and side effects in every 2 treatment cycles. Result: The effective rate of the patients in the observation group had no different with that of the control group (64.7% to67.6%)(P>0.05),the improvement of quality of life in the observation group was better than that of the control group, and the difference was statistically significant (P<0.05),the incidence of leukocyte decline, abdominal pain and nausea in the observation group were significantly lower than
those in the control group (P<0.05), and the difference was statistically significant. Conclusion: Aidi injection combined with paclitaxel and cisplatin is safe and effective in the treatment of advanced epithelial ovarian cancer. Compared with chemotherapy alone, it improves the life and does not increase toxicity.


Keywords


Advanced epithelial ovarian cancer, Aidi injection; Paclitaxel, Cisplatin


DOI
10.12783/dtbh/icmsb2018/25409

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