Eudragit E100 Nanofibers Fabricated with Varied Solvent Mixtures as the Sheath Working Fluids During Electrospinning

JIAO-JIAO LI, YAO-YAO YANG, KE WANG, DENG-GUANG YU

Abstract


It is still a big concern that how to manipulate the nanofibers’ diameters in an accurate manner. The most recently reported modified coaxial electrospinning, where un-spinnable solvent could be tried as a sheath fluid, is a potential method to achieve this goal. In this study, with Eudragit E100 at a concentration of 15 wt. % in a mixture of ethanol/N, N-dimethylformamide with a volume ratio of 8:2 as the core fluid, a varied of mixed organic solvents were exploited as the sheath fluids to manipulate the sizes of electrospun Eudragit nanofibers. The scanning electron microscopic results demonstrated that the nanofibers’ diameter (D, μm) had a clear exponential relationship with the DMF content (C, %) in the sheath mixtures as D=1.434 - 0.023 C (R=-0.9976) within a rage between 0% to 30%. The microformation mechanism was suggested. The present investigations paved a new way for implementing the modified coaxial processes, which can be utilized to manipulate the diameters of nanofibers robustly and stably.

Keywords


Modified coaxial electrospinning, Nanofiber, Microformation mechanism, Eudragit E100, Sheath solvent.


DOI
10.12783/dtbh/icmsb2017/17943

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