The Separation of Isoliquiritigenin by Manual Three-zone Simulated Moving Bed Chromatography

Jing-Xiang CONG, Shao-Yan WANG, Jing-Yang LIU, Xian-Li WANG

Abstract


Isoliquiritigenin is one of major active component in licorice, which plays an important role in pharmaceutical fields. It was purified by a three-zone simulated moving bed (SMB) at laboratory scale in this paper. The comparison of the isoliquiritigenin separation with different column configurations was shown that the highest purity product was achieved in 1:1:2 configuration mode. It was obtained 99% in final purity of isoliquiritigenin by combing with partial collection method, which is potentially useful for the purification of target product from multi-components sample.

Keywords


Three-zone Simulated Moving Bed, Isoliquiritigenin, Separation


DOI
10.12783/dteees/edep2016/5953

Full Text:

PDF

Refbacks

  • There are currently no refbacks.